Acute Allergic Reactions to mRNA COVID-19 Vaccines

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Anaphylaxis to the mRNA COVID-19 vaccines is currently estimated to occur in 2.5 to 11.1 cases per 1 million doses, largely in individuals with a history of allergy. Allergic concerns contribute to vaccine hesitancy; we investigated acute allergic reaction incidence after more than 60 000 mRNA COVID-19 vaccine administrations.

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Blumenthal-2021-Vaccine-Allergic-Reactions.pdf

Author(s)

  • Kimberly G. Blumenthal, MD, MSc, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston

Collaborator(s)

  • Lacey B. Robinson, MD, MPH, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston
  • Carlos A. Camargo Jr, MD, DrPH, Department of Emergency Medicine, Massachusetts General Hospital, Boston
  • Erica S. Shenoy, MD, PhD, Division of Infectious Diseases, Massachusetts General Hospital, Boston
  • Aleena Banerji, MD, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston
  • Adam B. Landman, MD, Department of Emergency Medicine, Brigham and Women’s Hospital, Boston, Massachusetts
  • Paige Wickner, MD, MPH, Division of Allergy and Clinical Immunology, Brigham and Women’s Hospital, Boston, Massachusetts

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